A clinical trial to study the effects of a resin modified fluoride varnish in preventing white spot lesions during fixed orthodontic treatment

Resin modified glass ionomer cement varnish in preventing white spot lesions during orthodontic therapy â?? a combined in vitro and in vivo study

Status

Recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/04/013085

Enrollment

400

Registered

2018-04-06

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Adolescent patients from age 12-20 years who require fixed orthodontic treatment with full arch bonding of upper and lower arches

Interventions

Intervention1: application of varnish to a selected quadrant during the course of fixed orthodontic treatment: varnish application to be monitored for effects after 3 months of application Control Int

Eligibility

Inclusion criteria

Inclusion criteria: GROUP 1 1. Patients in the age range of 12-20 years requiring comprehensive orthodontic treatment with fully erupted maxillary and mandibular teeth GROUP 2 1. Age less than 20 years (higher incidence of caries during teenage years) 2. Premolars fully erupted and intact without visible defects on their buccal surfaces 3. Patients with aligned arches who require extraction of first premolars only during the stage of retraction (eg.class I bimaxillary proclination)

Exclusion criteria

Exclusion criteria: Any subject with enamel hypoplasia due to fluorosis, discolourations, severely malposed teeth and with any systemic diseases and syndromes

Design outcomes

Primary

Measure	Time frame
application of resin modified glass ionomer cement varnish will have a favourable effect in the prevention of white spot lesions during orthodontic treatment clinically and microscopicallyTimepoint: application of resin modified glass ionomer cement varnish will have a favourable effect in the prevention of white spot lesions during orthodontic treatment clinically and microscopically	—

Secondary

Measure	Time frame
application of resin modified glass ionomer cement varnish will have a favourable effect in the prevention of white spot lesions during orthodontic treatment clinically and microscopicallyTimepoint: 6 months	—

Countries

India

Contacts

Public ContactNIMZIYA K N

MALABAR DENTAL COLLEGE AND RESEARCH CENTRE

bejoyunni@gmail.com9846126527

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026