Health Condition 1: null- EXTENSIVE DERMATOPHYTIC INFECTIONS
Conditions
Interventions
Intervention1: ITRACONAZOLE: Group A - systemic Itraconazole 5 mg/kg body weight (BW) once daily for a period of 6 weeks.
Control Intervention1: GRISEOFULVIN: Group B â?? Griseofulvin 10 mg/kg Body we
Sponsors
MAHARAJAHS INSTITUTE OF MEDICAL SCIENCES
Eligibility
Inclusion criteria
Inclusion criteria: 1.Clinically diagnosed cases of extensivedermatophytoses infection affecting more than one region of the body. 2. Both sexes between the age groups 18 - 70 yrs 3.Patients who have not used topical and systemic antifungal drugs for the past 6 weeks.
Exclusion criteria
Exclusion criteria: 1.Infants, below 18 yrs, above 70 yrs 2.Immunocompromised patients including HIV are excluded. 3.Pregnancy and lactating patients are excludued. 4.Patients receiving multiple drugs for medical conditions including glucocorticosteroids.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Cinical profile of dermatophytic infections prevalent in this region will be noted. 2. Mycological profile of dermatophytic infections including species identification prevalent in this region will be noted. 3. Sensitivity pattern of isolates against terbinafine, itraconazole,griseofulvin will be studied and recorded. 4. Therapeutic efficacy of single and in combinations of systemic antifungal drugs in extensive dermatophytic infections will be reported. Timepoint: 8 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To note the recurrences in the follow up period of 6 months.Timepoint: 6 months | — |
Countries
India
Contacts
Public ContactVanapalli Ramani Sneha
Maharajahs Institute Of Medical Sciences
Outcome results
None listed