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To study the efficacy of toothpastes in teeth sensitivity

A Clinical trial to evaluate the efficacy and comparison of a dentifrice containing Sodium Fluoride; 8% Strontium Acetate, Strontium Acetate (in Herbal Base) and two different Herbal dentifrices in reducing Dentinal Hypersensitivity

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/04/013038
Enrollment
140
Registered
2018-04-04
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K038- Other specified diseases of hard tissues of teeth

Interventions

Intervention1: Toothpaste B: Active ingredients: Strontium acetate, Gairic powder, Herbal extract (Anacyclus pyrethrum, Piper nigrum, Piper longum, Zingiber officinale, Zanthoxylum armatum) The produc

Sponsors

Dabur India Limited
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Subjects with dental hypersensitivity complaints

Exclusion criteria

Exclusion criteria: 1. Subjects who had dental pathology causing pain similar to cervical dentinal hypersensitivity (such as teeth with caries, the presence of orthodontic appliances and restorations and/or the presence of a history of periodontal surgery in the area of the tooth during the previous three months) 2. Subjects who had taken any medication 3. Subjects who received professional treatment with desensitizing agents in the previous six months 4. Subjects who received any treatment in the past 3 months 5. Subjects who were pregnant or lactating 6. Subjects who had any systemic diseases and/or the presence of a vital bleaching history

Design outcomes

Primary

MeasureTime frame
Reduction of dentin hypersensitivity immediately after a single self-application, as well as after a subsequent twice daily brushing for a period of 6 weeksTimepoint: Baseline, 60 seconds, 3 weeks, 6 weeks

Secondary

MeasureTime frame
NilTimepoint: Nil

Countries

India

Contacts

Public ContactDr Sonia Datta

Inderprastha Dental College & Hospital

pankajdatta97@gmail.com01204176700

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026