Health Condition 1: null- Diabetes mellitus type 2 with diabetic retinopathy
Conditions
Interventions
Intervention1: Calcium Dobesilate: 500 mg orally three times daily for 12 weeks
Control Intervention1: Placebo Tablet: Orally three times daily for 12 weeks.
Sponsors
Jawaharlal Nehru Medical College
Eligibility
Inclusion criteria
Inclusion criteria: Patients with Diabetic Retinopathy
Exclusion criteria
Exclusion criteria: 1.Previous intra-ocular surgery, 2.Ocular trauma, 3.Ocular inflammation, 4.Glaucoma, 5.Laser photocoagulation within past 4 wks 6.Systemic inflammation 7.Corticosteroids within past 4 wks 8.Pregnancy (first trimester) / lactation 9.Severe renal/ liver impairment 10.Hematological disease 11.Vitamin / mineral supplements (including herbal drugs) within past 4 wks 12.Malignancies or history of chemotherapy or radiotherapy within past 1 year. 13. Recipients of bone marrow or organ transplant
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in levels of: 1.Interleukin IL- 1β 2.Interleukin IL-6 3.Interleukin IL-10 4.TNFα Timepoint: Baseline and 12 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in macular thicknessTimepoint: Baseline and 12 weeks | — |
Countries
India
Contacts
Public ContactDr Namita Sharma
Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh
Outcome results
None listed