Health Condition 1: null- ASA Grade I & II patients
Conditions
Interventions
Intervention1: Injection Dexmedetomidine: 1mcg/kg dexmedetomidine in 100 ml Normal Saline over 10 minute given before induction of anesthesia
Control Intervention1: Normal Saline: 100 ml Normal Saline
Sponsors
ESIPGIMSR and Model hospital andheri
Eligibility
Inclusion criteria
Inclusion criteria: Patient posted for surgery under general anesthesia. Patients belonging to ASA class I & II.
Exclusion criteria
Exclusion criteria: 1 Patients with hypertension, cardiac, respiratory, renal, hepatic & cerebral diseases 2. Patients with difficult airway and obese patients. 3. Patients with endocrinal diseases like hyperthyroidism, hypothyroidism and diabetes mellitus. 4. Pregnant patient
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.To study the efficacy of 1μg/kg dexmedetomidine intravenous given in 100 ml NS over 10 minutes before induction to obtund the pressor response of laryngoscopy and tracheal intubation with respect to- Heart rate, systolic blood pressure, diastolic blood pressure, Mean arterial pressure.Timepoint: Baseline, at 5 and 10 mins during drug infusion, after induction, at and 5,10 mins after intubation | — |
Secondary
| Measure | Time frame |
|---|---|
| To study any adverse effects associated, such as perioperative hypotension, bradycardia.Timepoint: Baseline, at 5 and 10 mins during drug infusion, after induction, at and 5,10 mins after intubation | — |
Countries
India
Contacts
Public ContactDr Sandhya Gujar
ESIPGIMSR and Model hospital Andheri east Mumbai
Outcome results
None listed