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effect of numbing the nerve supplying the lower jaw for cancer surgery on the jaw

Inferior alveolar nerve block for intraoperative analgesia for maxillofacial cancer surgery requiring unilateral mandibular resection- A randomized controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/04/012996
Enrollment
50
Registered
2018-04-04
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- All adult patients below 75 yrs, ASA I and II PS requiring maxillofacial cancer surgery requiring unilateral mandibular resection and unilateral neck dissection

Interventions

Intervention1: Inferior alveolar nerve block: Study procedure: A long acting local anaesthetic agent Inj Bupivacaine hydrochloride 0.5% (2 ml) will be given after induction of anaesthesia by open mou

Sponsors

Tata Memorial Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: INCLUSION CRITERIA - All patients between the age of 18 and 75 yrs classified as ASA I and II physical status requiring maxillofacial cancer surgery requiring unilateral mandibular resection and unilateral neck dissection

Exclusion criteria

Exclusion criteria: EXCLUSION CRITERIA : - surgery involving upper alveolar / maxillary resection - patients with BMI below 18kg/m2 and above 30kg/m2 - allergy to local anaesthetic agent - Inability to give inferior alveolar nerve block due to any cause e.g. o restricted mouth opening o obscured landmark or infection at site - pregnant women - patients unable to give valid consent e.g. patients with learning difficulties - patients on medications for hypertension - patients with preoperative pain requiring regular pain medications - uncontrolled haemodynamic status e.g. baseline arterial blood pressure above 160 /90 and baseline HR above 100 /min

Design outcomes

Primary

MeasureTime frame
1.PRIMARY ENDPOINT â?? IV fentanyl requirement during primary tumour removal in the 2 groups Timepoint: Time of completion of primary tumour removal—

Secondary

MeasureTime frame
1.IV fentanyl requirement during neck dissection and primary tumour removal 2.Maximum change in heart rate from baseline during primary tumour removal 3.Maximum change in blood pressure from baseline during primary tumour removal 4. Need for rescue analgesics or vasoactive agents during primary tumour removal Timepoint: 1.Time of completion of primary tumour removal 2. Time of completion of neck dissection—

Countries

India

Contacts

Public Contactmadhavi shetmahajan

Tata Memorial Hospital

dr.maya.kamalakar@gmail.com02224177054

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026