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Study comparing combination of three drugs, sevoflurane with fentanyl and desflurane with fentanyl(drugs used for giving anesthesia)based on time taken for coming out of anesthesia after stopping their use.

To compare desflurane-fentanyl and sevoflurane-fentanyl on awakening time and airway morbidity in ambulatory surgery using a laryngeal mask airway- a randomised single blinded study.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/04/012993
Enrollment
70
Registered
2018-04-03
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- STABLE

Interventions

Intervention1: Desflurane with Fentanyl: Effect of Desflurane with Fentanyl on awakening time and airway morbidity in ambulatory surgery using laryngeal mask airway. Control Intervention1: Sevoflurane

Sponsors

Max Superspeciality hospital
Lead Sponsor
Max Superspeciality Hospital
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients undergoing ambulatory surgery 2.Age between 18-60 years 3.ASA grade 1 and 2 4.Expected duration of surgery less than 90 minutes 5.Patient with adequate mouth opening as defined by Mallampati scores(I &II) 6.Patient with adequate NPO status(as per ASA guidelines)

Exclusion criteria

Exclusion criteria: 1.Patient refusal to participate in the study 2.Patients 60 years of age 3.Pregnancy 4.ASA 3 and 4 patients 5.Patients with full stomach 6.Patients taking CNS depressants 7.Patients with psychiatric disorders 8.Chronic opioid or corticosteroid use 9.Patients with liver or renal disease 10.Obese patients ( Body mass index >35kg/m2) 11.Patients with upper airway morbidity (symptoms suggestive of URTI including cough, scratchy throat and hoarseness). 12.Patients with Mallampati scores III &IV 13.H/o of asthma 14.H/o of gastritis

Design outcomes

Primary

MeasureTime frame
1.Total time duration for awakening after discontinuation of volatile anaesthetic agent. 2.Incidence of cough determined through scores after discontinuation of the volatile anaesthetic agent. Timepoint: 1.Specific time when subject spontaneously opens his eyes after discontinuation of anesthetic agent 2.Incidence of cough determined after patient being shifted to PACU.—

Secondary

MeasureTime frame
1.Total duration of time to follow commands by protruding tongue after discontinuation of volatile anaesthetic agent. 2.Total duration of time to develop coherent speech after discontinuation of volatile anaesthetic agent. Timepoint: Time duration after discontinuation of volatile anaesthetic agent.—

Countries

India

Contacts

Public ContactDr Sansaya Mahapatra

Max Superspeciality Hospital

raj.tobin@maxhealthcare.com8130840480

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026