comparison of intrarticular injection vs nerve block for patient undergoing knee ligament surgery

Comparison of intra articular injection and femoral nerve block with levobupivacaine and clonidine for post operative analgesia after arthroscopic anteriorcruciate ligament reconstructionâ?? A randomized double blind clinical study

Status

Recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/04/012991

Enrollment

Registered

2018-04-03

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- acl tear ortho

Interventions

Intervention1: 1. Inj. Clonidine 30mcg 2. Inj .0.25 % levobupivacaine. These drugs are approved for nerve block and intra articular injection by drug controller general of India. : GROUP 2- receive

Eligibility

Inclusion criteria

Inclusion criteria: 1. All the patients belonging to ASA I or II undergoing Anterior cruciate ligament reconstruction in age group between 18-60 years under spinal anaesthesia.

Exclusion criteria

Exclusion criteria: 1. Known allergies to local anaesthetic agents. 2. Local infection at site of injection. 3. Patient on oral anti coagulant drugs. 4. BMI > 35 kg/m2

Design outcomes

Primary

Measure	Time frame
To compare the quality of post operative analgesia of ultrasound guided femoral nerve block with levobupivacaine / clonidine combination and intra articular administration of levobupivacaine /clonidine combination for patient undergoing ACL reconstruction under spinal anaesthesiaTimepoint: To compare the quality of post operative analgesia of ultrasound guided femoral nerve block with levobupivacaine / clonidine combination and intra articular administration of levobupivacaine /clonidine combination for patient undergoing ACL reconstruction under spinal anaesthesia	—

Measure

Time frame

To compare the quality of post operative analgesia of ultrasound guided femoral nerve block with levobupivacaine / clonidine combination and intra articular administration of levobupivacaine /clonidine combination for patient undergoing ACL reconstruction under spinal anaesthesiaTimepoint: To compare the quality of post operative analgesia of ultrasound guided femoral nerve block with levobupivacaine / clonidine combination and intra articular administration of levobupivacaine /clonidine combination for patient undergoing ACL reconstruction under spinal anaesthesia

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Secondary

Measure	Time frame
To compare time for first rescue analgesia. To compare total number of time and total number of breakthrough analgesics given during first 24 hours of post operative period. To note adverse effects like nausea , vomiting, motor weaknessTimepoint: To compare time for first rescue analgesia. To compare total number of time and total number of breakthrough analgesics given during first 24 hours of post operative period. To note adverse effects like nausea , vomiting, motor weakness	—

Measure

Time frame

To compare time for first rescue analgesia. To compare total number of time and total number of breakthrough analgesics given during first 24 hours of post operative period. To note adverse effects like nausea , vomiting, motor weaknessTimepoint: To compare time for first rescue analgesia. To compare total number of time and total number of breakthrough analgesics given during first 24 hours of post operative period. To note adverse effects like nausea , vomiting, motor weakness

—

Countries

India

Contacts

Public ContactASHWIN S JOHN

pondicherry institute of medical sciences

ranjanrv2005@gmail.com9600318905

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026