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Comparison of Dexmedetomidine with Magnesium Sulphate for preventing the increase in blood pressure and heart rate that occur at the time of endotracheal tube insertion in adult patients

Comparison of infusion Dexmedetomidine with Magnesium Sulphate for attenuation of the haemodynamic response during endotracheal intubation in adult patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/04/012985
Enrollment
156
Registered
2018-04-03
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- AGE 18-60YEARS OF EITHER SEX, ASA GRADE I AND II

Interventions

Intervention1: Dexmedetomidine infusion before induction of anaesthesia for attenuation of endotracheal intubation response: Just before induction of anaesthesia dexmedetomidine (1 ucg/kg)in 50ml of N

Sponsors

Vardhman Mahavir Medical College and Safdarjung Hospital New Delhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA grade I & II patients with mallampatti grades I & II

Exclusion criteria

Exclusion criteria: 1)Allergy to study medication 2)Difficult airway or Intubation time more than 20 seconds or more than one attempt 3)Hypertensive,Cardiac,Hepatic,Renal,Endocrine,Psychiatric disease & Morbid obesity 4) Pregnant & Nursing women

Design outcomes

Primary

MeasureTime frame
To compare the efficacy of infusion Dexmedetomidine with magnesium sulphate on haemodynamic parameters (HR & BP) during endotracheal intubation in adult patientsTimepoint: At the time of intubation—

Secondary

MeasureTime frame
To study the effect of dexmedetomidine & magnesium sulphate on: 1)Sedation 2)Requirement of neuromuscular blocking agent 3) Recovery characteristics Timepoint: At the time of intubation, during the surgery, and post operative period—

Countries

India

Contacts

Public ContactDr Nikita Choudhary

Vardhman Mahavir Medical College and Safdarjung Hospital

doctorrajpal04@gmail.com9911858311

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026