Comparison Between Two Local Anaesthetics Given In Interpleural Block For Control Of Pain In Patients Undergoing Breast Surgery

A Comparative Study Between 0.5% Ropivacaine And 0.5% Levobupivacaine For Post-operative Analgesia In Interpleural Block In Patients Undergoing Breast Surgery

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/04/012981

Enrollment

Registered

2018-04-03

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- 18 YEARS TO 65 YEARS OLD PATEINTS UNDERGOING BREAST SURGERY FOR MALIGNANT OR BENIGN CONDITIONS UNDER ASA GRADE I and II

Interventions

Intervention1: 0.5% LEVOBUPIVACAINE GROUP: Patients in this group will be induced using standard general anaesthesia technique.After induction in the supine position, Interpleural block will be given

Eligibility

Inclusion criteria

Inclusion criteria: 1)ASA grade I and II 2)Age between 18 to 65 years 3)Patients scheduled for elective surgery under general anaesthesia for any lesion in the breast benign or malignant

Exclusion criteria

Exclusion criteria: 1)Patients with history of allergy to local anaesthetics 2)Patients with severe renal,hepatic,respiratory,cardiac,neurologic disorders 3)patients with history of opiod,cocaine abuse 4)Patients on anticoagulants 5)Patients with psychiatric illness

Design outcomes

Primary

Measure	Time frame
1)To find out whether levobupivacaine is better than ropivacaine in interpleural block in providing longer duration of analgesia in patients undergoing breast surgery 2)Total number of rescue analgesics required in post -operative 24 hours by patients of each group 3)Total no of times fentanyl was givenn intraoperatively after induction in each group Timepoint: 1)To find out whether levobupivacaine is better than ropivacaine in interpleural block in providing longer duration of analgesia in patients undergoing breast surgery 2)Total number of rescue analgesics required in post -operative 24 hours by patients of each group 3)Total no of times fentanyl was givenn intraoperatively after induction in each group	—

Measure

Time frame

1)To find out whether levobupivacaine is better than ropivacaine in interpleural block in providing longer duration of analgesia in patients undergoing breast surgery 2)Total number of rescue analgesics required in post -operative 24 hours by patients of each group 3)Total no of times fentanyl was givenn intraoperatively after induction in each group Timepoint: 1)To find out whether levobupivacaine is better than ropivacaine in interpleural block in providing longer duration of analgesia in patients undergoing breast surgery 2)Total number of rescue analgesics required in post -operative 24 hours by patients of each group 3)Total no of times fentanyl was givenn intraoperatively after induction in each group

—

Secondary

Measure	Time frame
1)Any complications of the block or pertaining to drugTimepoint: post-operative 24 hrs	—

Countries

India

Contacts

Public ContactDR MONA SWAIN

VARDHMAN MAHAVIR MEDICAL COLLEGE AND SAFDARJUNG HOSPITAL

gogiaanoop@gmail.com9810318291

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026