Health Condition 1: null- PATIENTS UNDERGOING LAPAROSCOPIC SURGERY
Conditions
Interventions
Intervention1: Administration of either ondansetron, palonosetron or granisetron: Prophylactic administration of either ondansetron, palonosetron or granisetron prior to induction agent by Intravenou
Sponsors
BPS GMC Khanpur Kalan
Eligibility
Inclusion criteria
Inclusion criteria: 1.ASA grade I/II patients. 2.Patient receiving general anaesthesia for laparoscopic surgery
Exclusion criteria
Exclusion criteria: 1.Refusal to participate in the study 2.Patients less than 18 or more than 65 years of age 3.Pregnant and lactating females 4.Morbid obesity (BMI >40 kg/m2) 5.Allergy to any of the anti-emetic drugs 6.History of PONV and motion sickness 7.Use of anti-emetic medication within 6 h prior to surgery 8.Use of high dose opioids prior to surgery 9.Patients with history of motion sickness, endocrine or metabolic disorders, hepatic or renal disease, gastrointestinal disorders and psychiatric diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate and compare the efficacy of ondansetron with palonosetron, and ondansetron with granisetron in prevention of Post-Operative Nausea and Vomiting (PONV). Timepoint: prevention of nausea and vomiting for upto 24 hours after surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To compare the side effect and haemodynamic profile on use of ondansetron, palonosetron and granisetron in patients undergoing laparoscopic surgeries under general anaesthesia. 2. To evaluate patient satisfaction scores. Timepoint: INTRAOPERATIVE AND 24 HRS POST OPERATIVE | — |
Countries
India
Contacts
Public ContactRuchika Kathuria
BPS GMC Khanpur Kalan
Outcome results
None listed