Health Condition 1: null- Cataract
Conditions
Interventions
Intervention1: Melatonin: Tablet melatonin 3mg orally 90 minutes before surgery
Control Intervention1: Diazepam: Tablet Diazepam 5mg orally 90 minutes before surgery
Sponsors
Sri Devaraj Urs Academy of Higher Education and Research
Eligibility
Inclusion criteria
Inclusion criteria: 1.Adult patients of either aged 50-80 years 2.Patients undergoing elective Phacoemulsification cataract surgery 3.Patients with American society of Anaesthesiologists (ASA) grade I-II
Exclusion criteria
Exclusion criteria: 1. Patients with sleep disorders, diabetes mellitus, depressive disorder, insufficient pupillary dilatation, nystagmus, deafness, allergy to study drugs, or expected compliance problems due to known psychiatric disease and epilepsy 2. Ongoing treatment with hypnotics, psychotropic drugs, non steroidal anti-inflammatory agents, beta blockers, coumarin derivatives and opioids within a week before admission
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Decrease in verbal anxiety score (VAS) , verbal pain score (VPS) and sedation scoreTimepoint: Before premedication (T1), 60 minutes after premedication (T2), during the operation period (T3) and also postoperatively before shifting them from the recovery room (T4). Sedation score will be assessed during performance of block. | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess the adverse effects using WHO causality assessment scale Timepoint: 60 minutes after drug administration | — |
Countries
India
Contacts
Public ContactSarala N
Sri Devaraj Urs Medical College
Outcome results
None listed