To study the effects of adding two different drugs to already used drug in spinal anaesthesia and to compare their side effects and efficacy

Comparison of intrathecal bupivacaine-fentanyl and bupivacaine-butorphanol combination for joint replacement surgeries

Status

Recruiting

Phases

Phase 3Phase 4

Study type

Observational

Source

CTRI

Registry ID

CTRI/2018/04/012945

Enrollment

500

Registered

2018-04-03

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- lower limb joint replacement surgeries

Interventions

Control Intervention1: 0.5 % bupivacaine 3ml with 25 mcg fentanyl and 0.5% bupivacaine 3ml with 25 mcg butorphanol: comparison of effects of intrathecal injection of 0.5% bupivacaine 3 ml with 25 mcg

Eligibility

Inclusion criteria

Inclusion criteria: ASA 1 or 2 patients posted for total knee and hip replacement surgeries

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
duration and onset of sensory and motor block and need for rescue analgesiaTimepoint: post operative analgesia upto 24 hours	—

Secondary

Measure	Time frame
Intrathecal bupivacaine fentanyl combination provides faster analgesia and motor blockade but for a shorter duration and more need for rescue analgesiaTimepoint: 24 hours	—

Countries

India

Contacts

Public ContactDr Aakriti aakriti

Sri guru ramdass institute of medical sciences and research vallah amritsar

drruchisgrd@gmail.com09814320805

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026