Health Condition 1: null- cirrhosis of liver
Conditions
Interventions
Intervention1: NIL: NIL
Control Intervention1: NIL: NIL
Sponsors
Kasturba Medical College
Eligibility
Inclusion criteria
Inclusion criteria: who undergo ARFI (acoustic radiation force impulse) elastography for measurement of LS and SS as well those who undergo upper GI endoscopy and platelet count measurement as a standard of care in evaluation for cirrhosis will be recruited in to the study.
Exclusion criteria
Exclusion criteria: Patients with ongoing gastrointestinal hemorrhage Portal vein thrombosis Intrahepatic malignancy Previous or current treatment for portal hypertension (beta blocker, TIPS/ balloon occluded retrograde transvenous obliteration), Pregnant women Those not giving consent will be excluded
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1)To evaluate Spleen stiffness v/s Varices Risk Score (liver stiffness, spleen size and platelet count) in predicting the presence of esophageal varices 2) To evaluate Spleen Stiffness v/s Varices Severity Score (liver stiffness, spleen stiffness and ascites) for grading the severity of esophageal varices with endoscopic grading as gold standard 3) Determination of SS cutoff values for detecting presence and high-risk varices in patients with cirrhosisTimepoint: primary outcome will be evaluated by 2018 september 30 | — |
Secondary
| Measure | Time frame |
|---|---|
| With ARFI actual, no sedation during the procedure, potential cost savings for the patient no discomfort pre and post procedure as with endoscopy as well could be if this could be developed as a standard diagnostic tool for evaluation.Timepoint: September 2018 | — |
Countries
India
Contacts
Public ContactDr Nadella Sindhu
Kasturba Medical College
Outcome results
None listed