Evaluating the effect of taking probiotic tablets on oral bacteria in orthodontic patients

Comparative evaluation of effect of probiotics on streptococcus mutans and sobrinus count in orthodontic patients

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/04/012930

Enrollment

Registered

2018-04-02

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients undergoing orthodontic treatment

Interventions

Intervention1: compare and evaluate effects of probiotic lactobacillus acidophillus on Streptococcus mutans and sobrinus in the plaque surrounding brackets in orthodontic patients: Pathogenic bacteria

Eligibility

Inclusion criteria

Inclusion criteria: 1 Patients undergoing orthodontic treatment with straight wire appliance 2 Patients undergoing orthodontic treatment with metallic brackets 3 Patients with permanent dentition 4 Patients with good oral hygiene

Exclusion criteria

Exclusion criteria: 1 Systemic illness 2 Patients presenting allergies and idiosyncratic responses to product ingredients 3 Patients with poor oral hygiene 4 Patients with no anti-inflammatory or antibiotics taken one month before the study

Design outcomes

Primary

Measure	Time frame
Reduction in streptococcus mutans and sobrinus count in orthodontic patientsTimepoint: 15 days	—

Secondary

Measure	Time frame
Reduction in whitespot lesions in orthodontic patientsTimepoint: 15 days	—

Countries

India

Contacts

Public ContactManu Mathew

Coorg Institute of Dental Sciences

drsanjusomaiah@yahoo.com9945527999

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026