Health Condition 1: null- Assessment of pain scores by PIPP tool for all inpatient babies undergoing ROP screening for the first time as per unit protocol.
Conditions
Interventions
Intervention1: Oral morphine at dose of 100mcg/kg will be given 1 hour before procedure along with first tropicamide eye drops: Oral morphine solution will be given at 1ml/kg, prepared by pharmacology
Sponsors
NONE
Eligibility
Inclusion criteria
Inclusion criteria: All inpatient babies satisfying the unit ROP screening protocol and undergoing screening for first time will be included after getting a written consent from parents / caretakers.
Exclusion criteria
Exclusion criteria: 1. Babies on mechanical ventilator 2. Babies already on study drugs for any other reason 3. Breastfeeding mother in methadone or other analgesics 4. Babies with ileostomy / colostomy. 5. Babies kept NPO for other medical / surgical illness 6. Congenital anomalies
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean pain score, (Median if not normally distributed) at 1 minute post procedure.Timepoint: 1 minute post procedure. | — |
Secondary
| Measure | Time frame |
|---|---|
| (i) Mean pain scores at 5min and 15min (ii) Adverse events will be recorded for 24 hours post procedure 1. Tachycardia (180 beats /min) 2. Apnea requiring intervention 3. Abdominal distension 4. Change in requirement of respiratory support (more than 20% increase in fio2 requirement, more than 10% increase in flow requirement, increase of 1 PEEP, new onset respiratory support or Mechanical ventilation requirement) Timepoint: 5 minutes , 15 minutes post procedure 24 hours monitoring for adverse events. | — |
Countries
India
Contacts
Public ContactPrakash Vinayagam
Madras Medical College
Outcome results
None listed