Health Condition 1: null- Patients undergoing craniotomy
Conditions
Interventions
Intervention1: infusion dexmedetomidine: Intravenous infusion dexmedetomidine-0.7 µg /kg/ hr was started 10 minutes before induction of anaesthesia of each patient and was continued throughout the s
Sponsors
Bangur Institute of Neurosciences
Eligibility
Inclusion criteria
Inclusion criteria: 1)Written informed consent of the patients. 2)ASA grade I and II. 3)Age between 18 â?? 60 years. 4)Patients of either sex. 5)Patients scheduled for craniotomy operations who are supposed to be operated within 3 hours.
Exclusion criteria
Exclusion criteria: 1)Patientsâ?? refusal. 2)ASA grade III and IV. 3)Patients allergic to study medications. 4)Patientsâ?? with thyroid disorder, Parkinsons disease, dysautonomia, Raynaudâ??s syndrome, cardiopulmonary disease, history of allergy to drugs used, history of chronic use of sedative and hypnotic drugs. i)History of conduction defect of heart. ii)Initial core temperature >37.5oC or iii)Obese patients with B.M.I >30. iv)Pregnant or lactating women. v)Renal or hepatic dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of patients suffered from post-operative shivering in each group.Timepoint: first 6 hr postoperative | — |
Secondary
| Measure | Time frame |
|---|---|
| 1)Number of patients required rescue drug for shivering in the post-operative period. 2)postoperative sedation 3)intra operative blood pressure and heart rate 4)any side effects like hypotension,bradycardia,nausea postoperativelyTimepoint: first 6 hr postoperative | — |
Countries
India
Contacts
Public ContactSaikat Niyogi
IPGMER
Outcome results
None listed