Health Condition 1: T479- Poisoning by, adverse effect of and underdosing of unspecified agents primarily affecting the gastrointestinal system
Conditions
Interventions
None listed
Sponsors
Saara Banu EPM
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients above 20 years with clinical symptoms of liver disease along with abnormal liver function test with History of intake of Complementary and Alternative Medicines or other drugs (prescribed drugs) for more than 2 months duration. 2.Both Male and female.
Exclusion criteria
Exclusion criteria: 1.Chronic Alcoholic hepatitis patients, infective hepatitis A patients. 2.Age less than 20 years. 3.Pregnant women & lactating mothers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. The levels of Oxidative stress (Superoxide dimutase, Malondialdehyde levels) in drug induced liver injury patients. 2. The levels of TGF-1 beta in drug induced liver injury patients. Timepoint: Superoxide dimutase, Malondialdehyde, TGF-1 beta levels - in patients serum collected within 24 hours of elevated liver function test. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Presence of Heavy metals like cadmium, copper, lead in drug induced liver injury patients using Atomic Absorption Spectrometry. 2.Nature of Complementary and Alternative Medicines which causing liver injury. Timepoint: Presence of copper or cadmium or lead using Atomic Absorption Spectrometry using patients serum collected within 24 hours of elevated liver function test. | — |
Countries
India
Contacts
Public ContactDr Saara Banu EPM
PSG Institute of Medical Science and Research
Outcome results
None listed