To compare 2 pain-reducing techniques, viz ultrasound guided injection of a painkiller drug around the peripheral nerve versus injection of painkiller drug around the spinal cord ,following excision of knee tumours

Comparison of Ultrasound guided femoro-sciatic nerve block versus epidural analgesia for post-operative analgesia following excision of knee tumours- A randomized control study.

Status

Active, not recruiting

Phases

Phase 1Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/03/012894

Enrollment

Registered

2018-03-27

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- KNEE TUMOURS Health Condition 2: C402- Malignant neoplasm of long bones of lower limb

Interventions

Intervention1: Ultrasound guided femoro-sciatic block: Femoro-sciatic block â?? 0.25% ropivacaine 20-25 ml with 0.5microgm/kg clonidine. postop rescue analgesic requirement for 24 hours. Control Inte

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA 1 TO 3 2. Weight more than 40kg 3. Surgery- Elective knee tumour excision surgery ,viz osteogenic sarcoma, GCT, Chondrosarcoma, Aneurysmal bone cyst, Ewings sarcoma

Exclusion criteria

Exclusion criteria: 1. Refusal to consent 2. Allergy to opioids , local anaesthetics 3. C/I to epidural and PNB 4. E/o severe cardiovascular , renal , hepatic diseases 5. Opioid drug abuse ï?· Inability to comprehend VAS pain assessment score ï?· Those who require amputation for knee tumour

Design outcomes

Primary

Measure	Time frame
VAS score for pain and total analgesic requirementTimepoint: 24 hours	—

Secondary

Measure	Time frame
Incidence of side effects- PONV, pruritis, neurological sequelae,local side effects, respiratory depressionTimepoint: 24 hours;Intraoperative hemodynamics and blood lossTimepoint: Intraoperative;Overall patient satisfaction for pain managementTimepoint: 24 hours	—

Countries

India

Contacts

Public ContactDr Dilip Shende

AIIMS

dilipshende@yahoo.com8800377697

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026