Comparison of dose of phenylephrine required to treat hypotension after spinal anaesthesia in parturients with normal and raised blood pressure

Phenylephrine for treatment of post-spinal hypotension in pre-eclamptic and normotensive parturients: A Pilot Study

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/03/012890

Enrollment

Registered

2018-03-27

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Full term pregnant females Health Condition 2: O140- Mild to moderate pre-eclampsia

Interventions

Intervention1: Phenylephrine 50 mcg: Phenylephrine boluses of 50 mcg will be administered to the parturients every minute till the normal BP is restored in both the groups if they develop hypotension

Eligibility

Inclusion criteria

Inclusion criteria: Previously healthy parturients with singleton term pregnancy

Exclusion criteria

Exclusion criteria: History of diabetes, cardiovascular and cerebrovascular diseases, placenta previa, abruptio placenta, fetal abnormalities, cord prolapse or nuchal cord, fetal malformations and those having any contraindication to Spinal anaesthesia

Design outcomes

Primary

Measure	Time frame
Total dose phenylephrine required to treat hypotensionTimepoint: Calculated once, after the delivery of the baby	—

Secondary

Measure	Time frame
The dose of phenylephrine required to treat the first hypotensive episodeTimepoint: Every 1 minute till the first hypotensive episode is treated successfully with phenylephrine	—

Countries

India

Contacts

Public ContactDr Rashmi Salhotra

University College of Medical Sciences and GTB Hospital, Delhi

rashmichabra@yahoo.com9911317334

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026