Health Condition 1: null- chronic low back ache
Conditions
Interventions
Intervention1: epidural injection: epidural steroid injections with either ketamine 50 mg or clonidine 75 microgram to be given in 60 patients with chronic low back ache with placebo group of 30 patie
Sponsors
Sri Guru Ram Das Institute of Medical Sciences and Research
Eligibility
Inclusion criteria
Inclusion criteria: Patients - sensory deficit without any major motor component - age group 18 to 70 years - history of low backache with or without radiculitis of minimum 3 months duration and -no relief with conservative treatment will be included in the study.
Exclusion criteria
Exclusion criteria: 1. Contraindications to epidural anaesthesia, such as local infections, generalised septicaemia, platelet and clotting factor abnormalities, significant neurological disease with motor or sensory deficit, diagnosed increased intracranial pressure 2. Contraindications to epidural ketamine like h/o psychiatric disorder, raised intracranial or intraocular pressure, h/o cardiovascular disorder or uncontrolled hypertension. 3. Contraindications to epidural clonidine like history of cardiovascular disease, history of postural hypotension or history of any psychiatric disorder. 4. A known history of allergy, sensitivity or any other form of reaction to local anaesthetics of amide type or opioids. 5. Psychiatric history or any other concomitant disease which may lead to unreliability. 6. Patients with spinal cord deformities like scoliosis, kyphosis in whom there is anticipated difficult epidural anaesthesia. 7. LESI done before enrolling patient for study 8. H/o spinal surgery 9. Caudaequina syndrome 10. Epidural lipomatosis 11. Opioid habituation 12. Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Relief of pain from baselineTimepoint: 50 percent pain relief from baseline at 3 months follow up | — |
Secondary
| Measure | Time frame |
|---|---|
| Reduction in number of repeat blocksTimepoint: reduction in number of repeat blocks at 3 months follow up | — |
Countries
India
Contacts
Public ContactDr Tavleen Kaur
Sri Guru Ramdas Institute Of Medical Sciences And Research Vallah Amritsar
Outcome results
None listed