Skip to content

study comparing levels of oral fluid contents in patients with sugar disease and gum disease before and after cleaning & laser light treatment

Comparative evaluation of lipid peroxidation levels in gingival crevicular fluid of chronic periodontitis patients with diabetes mellitus before and after scaling and root planing with photodynamic therapy as an adjunct A split mouth spectrophotometric study

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/03/012856
Enrollment
25
Registered
2018-03-26
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- patients who are known type 2 diabetic and diagnosed with chronic periodontitis

Interventions

Intervention1: Photo Dynamic Therapy: Split mouth design in this one quadrant with photo dynamic therapy on baseline, 7th day, 14th day and 21st day and other quadrant with out Photodynamic therapy Co

Sponsors

Sreelakshmi sekhar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Subject with confirmed diagnosis of type 2 diabetes (HbA1c levels above 6.5%) & on medication for the same. 2.Subject with minimum complement of 20 teeth. 3.Subjects with at least two non-adjacent sites with probing pocket depths (PPDs) of >= 5 mm.

Exclusion criteria

Exclusion criteria: 1.Patients with any other known systemic diseases other than diabetics. 2.Subjects who had undergone any periodontal treatment in the past 6 months. 3.Subjects who are tobacco or alcohol users. 4.Subjects who have received antibiotics/ anti-inflammatory drugs/ steroids in the past 6 months. 5.Pregnant or lactating women. 6.Subjects who are known allergic to the indocyanine green dyes 7.Subjects who change the medication &/or dose during the course of the study.

Design outcomes

Primary

MeasureTime frame
To assess the efficacy of PDT as an antimicrobial complement to scaling & root planing in individuals with type 2 diabetes mellitus by assessing the lipid peroxidation levels in GCF and HbA1c levels in bloodTimepoint: 3 months

Secondary

MeasureTime frame
reduction in inflammation and patient comfortTimepoint: 3 months

Countries

India

Contacts

Public ContactSreelakshmi sekhar

Rajiv Gandhi University of Health Sciences Bangalore

amitakw@rediffmail.com9480085687

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026