Assessing the effectiveness of cold local anesthesia in management of acute tooth pain

Evaluation of pain on injection, onset and anesthetic efficacy of precooled injection site and 2% lignocaine (4-6Ã?ÂºC) during maxillary infiltration in patients with symptomatic irreversible pulpitis - a randomized controlled trial

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/03/012834

Enrollment

Registered

2018-03-26

Start date

Unknown

Completion date

Unknown

Last updated

2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Symptomatic irreversible pulpitis, Hot tooth

Interventions

Intervention1: 8-10 degrees celcius cold lignocaine : Ice sticks will be used for surface anesthesia Control Intervention1: Room temperature lignocaine: Topical local anesthesia gel will be used for

Eligibility

Inclusion criteria

Inclusion criteria: Healthy adult patients aged 18 to 45 years who are willing to give informed consent Teeth with acute and spontaneous pain Patients with symptomatic irreversible pulpitis in maxillary molars of both the quadrants Presence of vital tissue on access opening

Exclusion criteria

Exclusion criteria: Allergic to Local anesthetics Medically compromised patients (ASA Class III or higher) Patients under medication which may affect the pain assessment Inability to give informed consent Teeth with presence of Periapical radiolucencies presence of active pathosis in the injection site vertical fractures periodontally compromised teeth nonrestorable teeth

Design outcomes

Primary

Measure	Time frame
Reduced pain on injection Faster onset of pulpal anesthesiaTimepoint: Onset - 1 minute after injection of anesthesia	—

Secondary

Measure	Time frame
Greater anesthetic efficacyTimepoint: 15 minutes	—

Countries

India

Contacts

Public ContactSekar Mahalaxmi

SRM Dental College, Ramapuram

researchmaha@gmail.com9381018598

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026