Health Condition 1: null- patients reporting to the department with periodontal disease
Conditions
Interventions
Intervention1: Scaling and root planing: The intervention in this trial is scaling and root planing which is mechanical cleaning,performed on all the subjects in both the groups only once. It has been
Sponsors
Department of Periodontics
Eligibility
Inclusion criteria
Inclusion criteria: At least 12 natural teeth present,Patients diagnosed with chronic periodontitis clinically & radiographically,Pocket probing depth (PPD) >= 5 mm,Willingness to comply with the study protocol.
Exclusion criteria
Exclusion criteria: Existing systemic disease that may influence the severity and/or progression of periodontitis. Patients with known/suspected allergy to statins. Patients on systemic statin therapy. Patients with a history of smoking and alcohol consumption. Systemic administration or local application of antibiotics within the previous six months. Oral debridement has been rendered within the previous 6 months.Pregnancy or lactation.Unable or not willing to comply with the study protocol.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluation of clinical parameter - Plaque index, Bleeding on probing, Clinical attachment level and Pocket probing depth. Evalution of Microbiological parameters- Gram staining and Phase contrast microscopy in group A and group BTimepoint: Evaluation of Clinical parameter at 21,30 and 60 days and Microbiological parameters at 7,14 and 21 days after drug delivery and scaling and root planing. | — |
Secondary
| Measure | Time frame |
|---|---|
| Whether Simvastatin local drug delivery and scaling and root planing has better outcome than only scaling and root planing.Timepoint: Clinical evaluation done at 60 days , Microbiological evaluation done at 21 days. | — |
Countries
India
Contacts
Public ContactAratrika Mukherjee
Sri Hasanamba Dental College and Hospital
Outcome results
None listed