Effect of folic acid on red,burning and ulcerated gums

Effect of Folic acid supplementation on Desquamative gingivitis

Status

Recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/03/012813

Enrollment

Registered

2018-03-23

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Desquamative Gingivitis

Interventions

Intervention1: Oral supplementation of tablet Folic acid 5mg once daily for 2weeks as an adjunct along with topical local steroid twice daily for 2 weeks.: Tablet Folic acid 5mg once daily as adju

Eligibility

Inclusion criteria

Inclusion criteria: Desquamative Gingivitis Lesion presenting as erythema, burning sensation, desquamation, ulceration of gingiva and associated oral mucosa

Exclusion criteria

Exclusion criteria: Dental plaque induced inflammatory diseases of gingiva such as gingivitis and periodontitis. Oral Candidiasis. Acute Herpetic gingivostomatitis. Acute Necrotizing ulcerative gingivitis.

Design outcomes

Primary

Measure	Time frame
1. Healing outcome of the lesion(Complete regression/partial regression/No Regression) 2.Change in the surface area of the lesion(mm2) 3. Visual analog score for assessing reduction in pain perception(0 to 10 scale) Timepoint: Baseline, 2 weeks post intervention	—

Secondary

Measure	Time frame
Plaque Index Gingival Index Bleeding on Probing(BOP) Salivary TNF-alpha Levels Timepoint: Baseline, 2 weeks postintervention	—

Countries

India

Contacts

Public ContactDr Saif Khan

Aligarh Muslim University Aligarh

saifgood@gmail.com919012875280

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026