To compare and evaluate the efficacy of natural and commercially available intracanal medicament using Cone Beam Computed Tomography.

Comparative Evaluation of effect of Calendula Officinalis and Calcium Hydroxide as Intracanal medicament on Periapical Lesion size using Cone Beam Computed Tomography: An In Vivo Study.

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/03/012782

Enrollment

Registered

2018-03-23

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- patients with endodontically involved teeth with periapical lesion greater than 3 mm

Interventions

Intervention1: Calendula officinalis: Intracanal medicament placement by Calendula officinalis followed by assessment of periapical lesion size using cone beam computed tomography - 1year clinical sur

Eligibility

Inclusion criteria

Inclusion criteria: Age group between 18-45 yrs . ASA I &II patients. Subjects with periapical lesion of size greater than 3mm. Patients will be selected based on the periapical index score with 3,4 and 5 preoperatively. Teeth indicated for root canal treatment with periapical lesion. Patient should not be under medication for past 8 hours.

Exclusion criteria

Exclusion criteria: Patients who are medically compromised or allergic to drugs or pollens. Pregnant and lactating women. Periodontally weak teeth. Root caries. Calcified rootcanals. Retreatment cases. Presence of Internal root resorption. Blunderbuss canal.

Design outcomes

Primary

Measure	Time frame
Reduction in size of periapical radiolucencyTimepoint: after 2 weeks	—

Secondary

Measure	Time frame
Complete resolution of periapical radiolucency by evaluating after 1 year.Timepoint: at the end of 1 year	—

Countries

India

Contacts

Public ContactNJ Nagaraj

SRM Dental college Ramapuram

researchmaha@gmail.com9381018598

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026