Health Condition 1: null- This prospective study will be conducted on total of 50 cases of bone marrow trephine biopsy specimens of Multiple Myeloma, diagnosed at our hospital.
Conditions
Interventions
Intervention1: study group: 50 cases of Multiple Myeloma on the diagnostic trephine bone marrow biopsy specimens that are archived in the Department of Pathology, dharamshila hospital, delhi within ap
Sponsors
Dharamshila Hospital and Research Centre
Eligibility
Inclusion criteria
Inclusion criteria: 50 cases Multiple Myeloma diagnosed at our hospital will be examined and studied.
Exclusion criteria
Exclusion criteria: The following cases are excluded- 1) Post Chemotherapy (CT) patients 2) Post Radiotherapy (RT) patients 3) Plasmacytoma cases 4) Plasma cell leukemia cases
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To estimate the proportion of the proliferating (Ki67 expressing) plasma cells in a series of patients with multiple myeloma.Timepoint: at the end of the every month within study duration | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinico-pathologic correlation of Ki-67 index with various parameters viz. age, sex, performance status, hematological parameters (hemoglobin, total leukocyte count, platelet count and E.S.R.), biochemical parameters (total protein, albumin, A:G ratio etc.), number of osteolytic lesions, the Durie-Salmon staging, the International staging system, plasma cell percentage, plasma cell infiltration pattern in bone marrow and degree of fibrosis in bone marrowTimepoint: at the end of the every month within study duration | — |
Countries
India
Contacts
Public ContactDr Kangana Sengar
Dharamshila Hospital and Research Centre
Outcome results
None listed