Comparative study of instilling balloon cuff of breathing tube inserted in the throat during when patient is made unconscious under anaesthesia with 3 different drugs on patients heart rate and blood pressure when reversed form anaesthesia

Comaparitive study of extubation response among three groups by instilling intracuff saline, alkalinised lignocaine and alkalinised lignocaine with dexamethasone. A prospective, double blinded randomized control trial

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/03/012730

Enrollment

Registered

2018-03-22

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- healthy patients scheduled for elective surgery under general anaesthesia

Interventions

Intervention1: Aklalinised lignocaine 40 mg: 2ml of 2 % lignocaine with 2 ml of saline and 1 ml of 8.4% soda bicarbonate. 5 ml instilled in the cuff once at the beginning of surgery. Tube with cuff re

Eligibility

Inclusion criteria

Inclusion criteria: patients undergoing superficial surgery under general anaesthesia requiring endotracheal intubation

Exclusion criteria

Exclusion criteria: pregnancy emergency surgeries uncontrolled co morbidities active URTI/LRTI

Design outcomes

Primary

Measure	Time frame
Extubation response once the surgery is completeld, starting from after reversal of neuromuscular blockadeTimepoint: Extubation response recorded every 2 minutes after giving reversal till the removal of the tube to a maximum of 15 minutes.	—

Secondary

Measure	Time frame
Bucking of patientTimepoint: Recorded from the end of surgery every 2 minutes until 10 minutes after shifting patient out of the OT;Post operative sore throatTimepoint: Stars from shifting patient out of the OT every 6 hours till 24 hours after surgery	—

Countries

India

Contacts

Public ContactDivya Dinakar A

KMC Manipal

arunhd2000@yahoo.com9008415858

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026