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Skin changes in patients of Diabetes Mellitus and prediction of long term diabetes induced complications in kidney and eye through examination of vessels over nail fold.

Study of cutaneous manifestations and nail fold capillaroscopic findings in cases suffering from Diabetes Mellitus and their correlation with Retinopathy and Nephropathy

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2018/03/012719
Enrollment
200
Registered
2018-03-21
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Diabetes Mellitus cases with cutaneous manifestations

Interventions

None listed

Sponsors

Ruchi Shah
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: • All type-II Diabetes Mellitus cases patients attending the Diabetic clinic conducted in O.P.D. 18 ,every Wednesday and daily Medicine (O.P.D.18) and Skin and V.D. O.P.D. having one or more of the following cutaneous manifestations: Vascular Damage: - Leg ulceration - Wet gangrene of the foot - Erysipelas like erythema - Diabetic dermopathy - Rubeosis Neurological Damage: - Diabetic foot - Diabetic foot ulcer Infections Obesity and hyperlipidemia related skin disease: - Acanthosis nigricans - Skin tags - Eruptive Xanthomas of the skin Treatment related Skin manifestations: - Insulin lipodystrophy - Allergic reactions to Insulin - Allergic reactions to oral hypoglycemic drugs Disease associations and genetic syndromes: - Reactive perforating collagenosis(Folliculitis) - Autoimmune disease - Genetic and other systemic disease Miscellaneous: - Granulomatous disorders(Necrobiosis Lipoidica) - Stiff skin and joints: Cheiroarthropathy Finger pebbles Sceleredema diabeticorum - Pruritus - Diabetic Bullae

Exclusion criteria

Exclusion criteria: • Other dermatologic diseases having relation with Metabolic syndrome like Psoriasis • Cases having Autoimmune diseases like Systemic Lupus Erythematosus, cleroderma, Systemic Sclerosis which can give rise to abnormal capillaroscopic findings. • Smoking • Cases with known liver disease or other multi-system disorders

Design outcomes

Primary

MeasureTime frame
â?¢To study the cutaneous manifestations of Diabetes mellitus â?¢To demonstrate nailfold capillaroscopy changes due to diabetic microangiopathy â?¢To study the correlation between cutaneous and systemic manifestations of Diabetic microangiopathy in terms of Retinopathy and nephropathy Timepoint: patients will be assessed at the time of enrollment in the study only.

Secondary

MeasureTime frame
To study the correlation between cutaneous and systemic manifestations of Diabetic microangiopathy in terms of Retinopathy and nephropathyTimepoint: patients can be followed up every 6 months for new manifestations and ophthalmic checkup

Countries

India

Contacts

Public ContactRuchi Shah

Medical College,Baroda

ruchshah294@gmail.com9601742444

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026