Skip to content

A study comparing a biomarker in serum of gum diseased patients with and without diabetes before and after treatment.

COMPARATIVE EVALUATION OF SERUM CERULOPLASMIN LEVELS IN CHRONIC PERIODONTITIS WITH AND WITHOUT TYPE II DIABETES MELLITUS PATIENTS BEFORE AND AFTER SCALING AND ROOT PLANING-A CLINICO-BIOCHEMICAL ANALYSIS.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/03/012669
Enrollment
40
Registered
2018-03-19
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Serum ceruloplasmin levels in chronic periodontitis with and without type II diabetes mellitus patients before and after scaling and root planing. Health Condition 2: E119- Type 2 diabetes mellitus without complications

Interventions

Intervention1: evaluation of ceruloplasmin levels before and after scaling and root planing in chornic periodntitis and diabetes: Ceruloplasmin is an acute phase reactant seen to increase in inflammat

Sponsors

Dr Rugma U Menon
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Subjects who are within the age of 35-60 years. 2. Subjects with periodontitis with >5mm pocket depth in greater than 30% of tooth surface. 3. Physician diagnosed type 2 diabetes of more than 3 months duration. 4. Currently under the care of a physician for diabetes management. 5. No change in diabetes related medications during 3 months duration prior to enrolment. Â

Exclusion criteria

Exclusion criteria: 1. Patients with any other systemic diseases or condition (other than type2 Diabetes Mellitus) which would influence the course of periodontal disease or treatment. 2. Patients with medical conditions that would require antibiotic prophylaxis for routine dental procedure. 3. Patients who have taken antibiotics in previous 3 months. 4. Pregnant or lactating women. 5. Patients using any form of tobacco products.

Design outcomes

Primary

MeasureTime frame
to assess and compare if ceruloplasmin levels is higher for patients with diabetes than without diabetes.Timepoint: 30days

Secondary

MeasureTime frame
For quick assessment of disease by biomarker levelsTimepoint: 1 month per patient

Countries

India

Contacts

Public ContactDr Rugma U Menon

Coorg institute of dental sciences

radika_b24@yahoo.co.in9742096982

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026