None listed
Conditions
Interventions
Intervention1: L-Amino acids mixture (essential and non-essential).
Manufactured by Ajinomoto North America Inc.: Amino acids are mixed as per the reference egg protein pattern and fed to the childr
Sponsors
Dr Anura V Kurpad
Eligibility
Inclusion criteria
Inclusion criteria: 1. Children ( 6-10 years ) who are chronically undernourished (non-edematous ) based on the recent 2007 WHO growth standards for school-age children. 2. Primary endpoint; Underweight defined by a z-score 3. Secondary end point; stunting defined by a z-score of 4. A z-score 5. Who are positive for any intestinal parasites. 6. Serum albumin concentrations (30-50 g/L), in childrens who tested positive for intestinal parasites.
Exclusion criteria
Exclusion criteria: The following will be exclusion criteria for the study; 1. Children who do not follow the above selection criterion will be excluded. 2. Who are malnourished with edema will be excluded from the study. 3. Severally malnourished/ or Healthy children. 4. Children who are suffering from any other (previously reported) illness like, heart, kidney, lungs etc. 5. Who feel uncomfortable to undergo the experimental procedure. 6. If parents do not allow their children to participate, will also be an exclusion criteria for the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To determine the protein requirements in chronically malnourished children of school-age (6-10y) using the minimally invasive indicator amino acid oxidation (IAAO) method. Timepoint: Two times points (each before treatment for parasites and after treatment for testing 2 different levels of protein (low and high)based on habitual dietary intake. | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess the impact of antiparasite treatment in the same chronically undernourished children on protein requirements. Timepoint: Two times points (each before treatment for parasites and after treatment for testing 2 different levels of protein (low and high)based on habitual dietary intake. | — |
Countries
India
Contacts
Public ContactDr Anura V Kurpad
St Johnâ??s Medical College
Outcome results
None listed