Finding the concenteration of desflurane to induce sleep in 50% of children and blocking spinal nerves affects the concenteration of the same

Determination of Minimum alveolar concentration of desflurane for maintaining BIS below 50 in children and the effect of caudal analgesia on it - Determination of Minimum alveolar concentration of desflurane for maintaining BIS below 50 in children and the effect of caudal analgesia on it

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/03/012658

Enrollment

Registered

2018-03-19

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- ASA I-II children in between1-8 years of age undergoing elective infra-umbilical surgery under general anaesthesia

Interventions

Intervention1: Group C: Group C Children were placed in left lateral position. Caudal block was performed with short beveled 23G needle using 0.75mLâ?¢kg-1 of 0.25% bupivacaine. Children were then tur

Eligibility

Inclusion criteria

Inclusion criteria: Forty-five children of ASA status I-II between the age group of 1-8 years scheduled for elective infra-umbilical surgery under general anaesthesia during the study period (May 2014 to December 2014) were assessed for eligibility.

Exclusion criteria

Exclusion criteria: Patients with history of respiratory or neurological disease were excluded from this study

Design outcomes

Primary

Measure	Time frame
Primary outcome of the study was to determine MACBIS50 of desfluraneTimepoint: After attainment of brain and alveolar equilibrium BIS of desflurane was recorded at an interval of 10 sec for 1 min	—

Secondary

Measure	Time frame
Success rate of LMA removal, incidence of coughing and airway complications were the secondary outcomes studied. Timepoint: observed intraoperatively	—

Countries

India

Contacts

Public ContactJeetinder Kaur Makkar

PGIMER

jeet1516@gmail.com8847288105

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026