To estimate and compare a biomarker in saliva in gum disease patients with and without diabetes before and after treatment.

Comparative Evaluation Of Salivary Sialic Acid Levels In Chronic Periodontitis Patients With And Without Diabetes Mellitus Before And After Scaling And Root Planing-A Specterophotometeric Study.

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/03/012649

Enrollment

Registered

2018-03-19

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Chronic Periodontitis With And Without Diabetes Mellitus Health Condition 2: E118- Type 2 diabetes mellitus with unspecified complications

Interventions

Intervention1: scaling and root planing: scaling and root planing to remove deposits from teeth. Control Intervention1: salivary sialic acid: Increased sialic acid concentrations have been reported

Eligibility

Inclusion criteria

Inclusion criteria: 1. Subjects age ranging from 35-55 years. 2. Subjects with minimum complement of 20 teeth. 3. Subjects who are diagnosed with chronic periodontitis with at least two non-adjacent sites with probing pocket depth (PPD/CAL) of >= to 5mm. 4. Subjects who are diagnosed with diabetes with random blood sugar (RBS) values (>=180mg/dl).

Exclusion criteria

Exclusion criteria: 1. Subjects who had undergone any periodontal treatment in the past 6 months. 2. Subjects who are smokers. 3. Subjects who have received antibiotics/ anti-inflammatory drugs/ steroids in past 6 months. 4. Pregnant and lactating women. 5. Subjects with history of cardiac diseases, malignancy or any other inflammatory disorders.

Design outcomes

Primary

Measure	Time frame
Sialic acid level will be decreased in chronic periodontitis patients with and without diabetes after scaling and root planingTimepoint: 30,60 .90 days	—

Secondary

Measure	Time frame
Reduction in inflammation and patient comfortTimepoint: 30 ,60 .90 days	—

Countries

India

Contacts

Public ContactDr Amit Walwekar

Coorg Institute Of Dental Sciences

amitakw@rediffmail.com940085687

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026