Health Condition 1: null- PCOS related infertility
Conditions
Interventions
None listed
Sponsors
PGIMER Chandigarh
Eligibility
Inclusion criteria
Inclusion criteria: 1. Women with PCOS related infertility based on Rotterdamâ??s criteria. 2. Age less than 40 yrs. 3. Normal serum prolactin and thyroid function tests.
Exclusion criteria
Exclusion criteria: 1. Patient is on any insulin-sensitizing agent or any lipid-lowering agent or any other drugs 2. Presence of any other endocrine disorder 3. Presence of anorexia nervosa or bulimia nervosa or any hypothalamic or pituitary dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ovulation with Clomiphene CitrateTimepoint: At day 10-11 of each cycle, trans-vaginal ultrasound done to look for the formation of dominant follicle. This is repeated for three consecutive cycles after ovulation induction with 50 mg, 100 mg and 150 mg clomiphene citrate. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Dose at which ovulation occurred. (50 mg/100 mg/150 mg) 2.Dose at which conception occurred. (50 mg/100 mg/150 mg). 3. Comparison between different PCOS phenotypes.Timepoint: 1. Transvaginal scan done on day 10-11 of each cycle to look for the formation of the dominant follicle after ovulation induction with 50 mg/ 100 mg/150 mg Clomiphene Citrate. 2. Conception recorded with urine pregnancy test or ultrasound during this period of 3 months. | — |
Countries
India
Contacts
Public ContactGarima Sachdeva
PGIMER, CHANDIGARH
Outcome results
None listed