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Effect of Xylitol chewing gums on oral bacteria

To evaluate the effect of use of chewing gum containing 100% xylitol on mutans streptococci salivary levels among dental students in bangalore city - a randomised controlled trial.

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/03/012632
Enrollment
60
Registered
2018-03-19
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: 100% xylitol chewing gums EPIC (Epic Industries Inc. CA, USA): Duration of 3 months, twice a day.Composition includes xylitol, gum base, citrus extracts, soy lecithin, gum Arabic, titan

Sponsors

The Oxford Dental College and Hospital
Lead Sponsor
Oxford dental college
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Subjects who did not have any active carious lesions. Subjects who were not on any systemic antibiotic medication, 3 months prior to the commencing of the study. Subjects available for the entire duration of the study, willing to participate were included in the study.

Exclusion criteria

Exclusion criteria: Subjects who had recent exposure to topical or systemic fluoride treatment. Subjects who were phenylketonurics. Subjects who had a history gastro-intestinal problems. Subjects who were habitual consumer of chewing gums. Subjects who were undergoing any orthodontic treatment at the time of the study.

Design outcomes

Primary

MeasureTime frame
the action of 100% xylitol chewing gums at the dose and frequency used in our study in reduction of mutans streptococci and this strategy can be used as a targeted caries-preventive measureTimepoint: 30, 60 , 90 days

Secondary

MeasureTime frame
Follow-up for measuring stretptococcus mutans count, salivary pH levels and buffering capacityTimepoint: 60 days and 90 days

Countries

India

Contacts

Public ContactVanishree N

Bangalore Institute of Dental Sciences

vansan25@gmail.com9880030208

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026