Health Condition 1: null- Scheduled for trans-sphenoidal pituitary surgery
Conditions
Interventions
Intervention1: Dexmedetomidine Group: Patients in this group received i.v. dexmedetomidine 1 µg/kg over a 10-min period before induction of anesthesia and 0.5µg/kg/hr by continuous i.v. infusion dur
Sponsors
PGIMER Chandigarh
Eligibility
Inclusion criteria
Inclusion criteria: 40 ASA I-II patients between 18-65 years of age, scheduled for elective trans-sphenoidal pituitary surgery
Exclusion criteria
Exclusion criteria: Patients with following conditions: 1.Decreased level of consciousness 2.Increased intracranial pressure 3.Risk of impending cerebral herniation 4.Anticipated elective postop ventilation 5.Co-existing intracranial lesions like aneurysms or arteriovenous malformations 6.Significant cardiovascular co-morbidity like unstable angina, recent myocardial infarction, coronary artery bypass surgery, refractory arrhythmias, severe hypertension, congestive heart failure, 7.Those with severe respiratory disease such as bronchial asthma 8.Those with body weight more than 130% of ideal body weight
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Haemodynamic changes in mean arterial blood pressure and heart rateTimepoint: During procedure-every 10 minutes | — |
Secondary
| Measure | Time frame |
|---|---|
| Bleeding in surgical fieldTimepoint: During procedure;Isoflurane requirementTimepoint: During procedure;Recovery parametersTimepoint: Immediate postop | — |
Countries
India
Contacts
Public ContactAparna Jain
Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh
Outcome results
None listed