A study to determine the efficacy of a mouth wash of Spermaecoce hispida powder against dental problems, plaque and gum swelling (inflammation)

Effect of Spermaecoce hispida and control (placebo) mouth wash formulations in dental plaque and gingivitis patients: A randomized double blind control Clinical trial

Status

Active, not recruiting

Phases

Phase 1Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/03/012607

Enrollment

100

Registered

2018-03-15

Start date

Unknown

Completion date

Unknown

Last updated

2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- 100 Patients voluntaries with plaque and gingivitis -mild to moderate and with history of no serious health condition will be selected

Interventions

Intervention1: Intervention agent-Spermaecoce hispida: Mouth wash of Spermaecoce hispida formulation will be dispensed in the form mouth wash. 5ml will be swished for 60 seconds, twice daily for 21 da

Eligibility

Inclusion criteria

Inclusion criteria: 1.Subjects have ability to understand and sign a consent form prior to the recruitment on the study. 2.Healthy patients 18-30 years 3.Subjects with mild to moderate gingivitis Marginal Index score >1.75 and Plaque Index >2.4. 4. Minimum 20 teeth should be present in the dentition, no visble sign of untreated caries. 5. Patient diagnosed with mild to moderate type of gingivitis. 6. Generally good health (no sign of periodontitis , no active caries and no soft tissue lesions, patient on any antibiotics therapy) 7.PatientÃ¢â?¬•s ability and willingness of subjects follow the study procedures and. attend all scheduled visits and successfully complete the study.

Exclusion criteria

Exclusion criteria: 1.Subjects taking antibiotics or any other drugs within last 3 months. 2.Pregnant women and lactating women. 3.Medically compromised patients 4.Patients have periodontitis and active caries 5.Patients with a know history of allergic to chemical or any herbal product 6.Smokers and compulsive tobacco chewers

Design outcomes

Primary

Measure	Time frame
Reduction in the Gingivitis scoresTimepoint: Intital scores of Modified gingival index (Lobene) compared to scores after 4 weeks.Interval of score : 0 day, 9th Day, 15th day and 21 st day	—

Secondary

Measure	Time frame
Reduction in the Plaque indexTimepoint: Plaque Index (Modified Quigley Hein Plaque Index) compared to scores after 4 weeks Interval of score: 0 day, 9th day, 15th day and 30th day	—

Countries

India

Contacts

Public ContactDr Chandrashekhar V M

PMNM Dental College and Hospital

shivwarad@gmail.com08354220435

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026