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Study aiming to decrease the incidence of aspiration and post operative sore throat in patients undergoing General Anaesthesia

Comparison of three endotracheal tube cuff inflation methods for adequate seal: A Randomized Clinical Trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/03/012600
Enrollment
120
Registered
2018-03-15
Start date
Unknown
Completion date
Unknown
Last updated
2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients to whom General Anaesthesia is aministered

Interventions

Intervention1: Optimize cuff pressures and volumes with supraglottic end tidal Co2 monitoring: Cuff is inflated or deflated until zero tracing is achieved by capnometry Control Intervention1: COMPARIS

Sponsors

JIPMER Intramural Funds
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All individuals with 18-60 years of age undergoing elective surgeries in JIPMER belonging to ASA class of 1 & 2 planned for general anaesthesia with orotracheal intubation.

Exclusion criteria

Exclusion criteria: 1 Patients undergoing laparoscopic surgeries 2 Patients who require elective ventilation post operatively and hence not extubated 3 Patients with high risk of aspiration preoperatively like GI obstruction including GOO, Achalasia cardia, etc. 4 Pre-existing laryngeal diseases 5 Patients expected to have profound hypotension during the surgery 6 Patients for whom rapid sequence intubation is planned

Design outcomes

Primary

MeasureTime frame
Initial Cuff inflation volumes, Cuff deflation volume during extubation, Cuff pressures initially and every 30min intra operatively, Initial and post optimization peak airway pressures.Timepoint: Cuff pressures every 30min

Secondary

MeasureTime frame
Postoperative sore throat will be graded as described by Figueredo et al. as follows: Grade 0: No sore throat Grade 1: Mild sore throat - Pain on swallowing solids Grade 2: Moderate sore throat - Pain on swallowing liquids Grade 3: Severe sore throat - Pain even on swallowing saliva Timepoint: 24 hours post operatively

Countries

India

Contacts

Public ContactDr MVS Satya Prakash

Jawaharlal Institute of Post Graduate Medical Education and Research

munaganuri1975@yahoo.co.in9786184626

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026