Health Condition 1: null- elective lumber spine surgery.
Conditions
Interventions
Intervention1: intranasal dexmedetomidine: intranasal dexmedetomidine at a dose of 1 mcg/kg body weight along with IV 0.9% normal saline infuse over 45 minutes before induction
Control Intervention1:
Sponsors
Bangur Institute of Neurosciences
Eligibility
Inclusion criteria
Inclusion criteria: 1)Patients with ASA physical status I and II. 2)Patients having Mallampati I and II 3)Patients in the age group between 18 to 60 years of age 4)Patients with body mass index (BMI) 5)Patients of either sex 6)Patients posted for elective lumber spine surgery under general anaesthesia
Exclusion criteria
Exclusion criteria: 1)Patients refusal to participate in the study 2)Known allergy or hypersensitive reaction to dexmedetommidine. 3)Patients suffering from significant cardiac disease e.g. IHD, cardiomyopathy, valvular disorder, hypertension, arrhythmia, etc. 4)Patients suffering from significant respiratory disease e.g. COPD, bronchial asthma, interstitial lung diseases, pneumonia etc. • Patients having metabolic, endocrinal, musculoskeletal, neurologic disorder or having major congenital anomalies. • History of drug abuse and/or psychiatric disorder
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| heart rate (HR), , respiratory rate (RR) and oxygen saturation (spO2) Baseline sedation status will be assessed by an observer using theRamsay sedation scale any other side effectTimepoint: at baseline then every 10 min intervals from intranasal dexmedetomidine administration in preinduction period, during induction, after intubation, every 1 min interval till 5mins and at 7 min and 10 min after intubation. Baseline sedation status will be assessed by an observer using theRamsay sedation scale before induction | — |
Primary
| Measure | Time frame |
|---|---|
| Mean arterial pressure (MAP)Timepoint: Mean arterial pressure (MAP) at baseline then every 10 min intervals from intranasal dexmedetomidine administration in preinduction period, during induction, after intubation, every 1 min interval till 5mins and at 7 min and 10 min after intubation. | — |
Countries
India
Contacts
Public ContactSaikat Niyogi
IPGMER
Outcome results
None listed