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A study of genetic profile and its relation with disease severity in psoriasis patients.

A study of miRNA223 expression and its correlation with disease severity in chronic plaque psoriasis patients.

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2018/03/012552
Enrollment
40
Registered
2018-03-13
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients with chronic plaque psoriasis

Interventions

Control Intervention1: NIL: NIL

Sponsors

Dr Bantwal Priya Baliga
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: CASES 1.Patients consenting to participate in the study. 2.All chronic plaque psoriasis adult patients above 18 years of age of either gender 3.All chronic plaque psoriasis patients diagnosed clinically or following biopsy will be included. 4. All chronic plaque psoriasis patients not treated with systemic immunosuppressant in the previous 3 months. 5. All chronic plaque psoriasis patient not treated with topical immunosuppressant in the previous 2 weeks. CONTROLS 1.Age and sex matched individuals without chronic plaque psoriasis.

Exclusion criteria

Exclusion criteria: CASES AND CONTROLS 1.Patients not consenting to participate in the study. 2.Patients with known autoimmune disease, malignancy, or serious chronic systemic disease.

Design outcomes

Primary

MeasureTime frame
Increased expression of miRNA223 in patients with chronic plaque psoriasisTimepoint: Expression of miRNA223 will be assessed within a period of 18 Months

Secondary

MeasureTime frame
The expression of miRNA223 can increase with the increase in severity of psoriasis.Timepoint: estimation of miRNA223 will be done after collection of all cases 18 months from the time of start of study

Countries

India

Contacts

Public ContactDr Bantwal Priya Baliga

K S Hegde Medical Academy

tones1980@yahoo.com9538986093

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026