Health Condition 1: null- ASTHMA IN CHILDREN Health Condition 2: J455- Severe persistent asthma
Conditions
Interventions
Intervention1: Magnesium Sulphate 2 ml (50% w/v) ampule, Levosalbutamol respules: Nebulisation of Magnesium Sulphate 2 ml (50% w/v) three times 20 minutes apart along with standard Levosalbutamol resp
Sponsors
Dr SRADHANANDA ROUT
Eligibility
Inclusion criteria
Inclusion criteria: 1.Age group 1-14years 2.Clinician diagnosed asthma 3.Moderate to Severe Acute Asthma Attack defined as PRAM Score >_ 5
Exclusion criteria
Exclusion criteria: 1.Patients who had life-threatening features [silent chest, cyanosis, bradycardia, arrhythmia, hypotension, coma,requiring intubation] 2. Any contraindication to either nebulised or intravenous Magnesium Sulphate [hepatic or renal failure, heart block, or known hypomagnesemia] Â 3. Medications containing Magnesium preparations in last 48 hours before recruitment. 4.Patients with alternative diagnosis [ Pneumonia ,pleural effusion etc.] Â
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duration of Hospital Stay And improvement in PRAM ScoreTimepoint: 2 years | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Need for oral and parenteral steroid 2.Duration of oxygen therapy 3.Trends in PEFR and FEV1 4. Need for ICU/ Intubation 5. Adverse effects if any ascribed to nebulised magnesium sulphate.Timepoint: 2 years | — |
Countries
India
Contacts
Public ContactDr SRADHANANDA ROUT
VEER SURENDRA SAI INSTITUTE OF MEDICAL SCIENCES AND RESEARCH
Outcome results
None listed