Health Condition 1: null- patients undergoing laparoscopic surgery under general anaesthesia
Conditions
Interventions
Intervention1: desflurane: inhalational anaesthetic agent
Control Intervention1: sevoflurane: inhalational anaesthetic agent
Sponsors
Director Principal
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age group between 18 and 60 years. 2. American Society of Anaesthesiologist (ASA) physical status I and II 3. Patients scheduled for elective laparoscopy surgery under general anaesthesia with duration of surgery less than 90 minutes.
Exclusion criteria
Exclusion criteria: 1. Patients with clinically significant cardiovascular, respiratory, hepato-renal, endocrine or metabolic disorders. 2. Patients with gastro-esophageal reflux disease. 3. Patients with neuropsychiatric disorders. 4. Patients with mental retardation. 5. Patients with a body mass index (BMI) > 35 kg.m.-2 6. Patients taking any central nervous system depressants. 7. Patients on chronic opioids, corticosteroids or any sleep aid drugs. 8. Patients having alcohol or any drug abuse. 9. Patients with any allergy to study drugs. 10.Pregnant and breastfeeding patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of emergence agitation by Aonos Four point ScaleTimepoint: 1.Immediately after the PLMA is removed in the Operating Room. 2.At admission in PACU. 3.Thereafter every 10 minutes in the recovery period, till the patient is discharged from PACU. | — |
Secondary
| Measure | Time frame |
|---|---|
| Any perioperative complicationsTimepoint: Perioperative period;Heart RateTimepoint: 1.Prior to induction 2.Ten minutes after induction. 3.After PLMA removal. 4.At admission in PACU. 5.Immediately Prior to discharge from PACU.;Mean Arterial PressureTimepoint: 1.Prior to induction 2.Ten minutes after induction. 3.After PLMA removal. 4.At admission in PACU. 5.Immediately Prior to discharge from PACU;Non Invasive Blood PressureTimepoint: 1.Prior to induction 2.Ten minutes after induction. 3.After PLMA removal. 4.At admission in PACU. 5.Immediately Prior to discharge from PACU;Quality of Recovery by QOR-40 score.Timepoint: 1.The day before surgery (baseline) 2.Postoperative day one (POD1,around 24 hours after surgery) 3.Postoperative day two (POD2, around 48 hours after surgery).;Saturation of Oxygen in Blood.Timepoint: 1.Prior to induction 2.Ten minutes after induction. 3.After PLMA removal. 4.At admission in PACU. 5.Immediately Prior to discharge from PACU.;Severity of anxiety using an 11-point numeric rating score (NRS)Timepoint: 1.In Preoperative room. 2.Immediately upon arrival in the PACU 3.Thereafter every 10 minutes in the recovery period, till the patient is discharged from PACU.;Severity of nausea/vomiting using an 11-point numeric rating score (NRS)Timepoint: 1.In Preoperative room. 2.Immediately upon arrival in the PACU 3.Thereafter every 10 minutes in the recovery period, till the patient is discharged from PACU.;Severity of pain using an 11-point numeric rating score (NRS)Timepoint: 1.In Preoperative room. 2.Immediately upon arrival in the PACU 3.Thereafter every 10 minutes in the recovery period, till the patient is discharged from PACU. | — |
Countries
India
Contacts
Public ContactDheeraj Kapoor
Government medical college and hospital, Chandigarh
Outcome results
None listed