Injection to treat joint problem in face

To assess the efficacy of prolotherapy in management of temporomandibular joint dysfunction.

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/03/012471

Enrollment

Registered

2018-03-12

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- TMJ dysfunction patients

Interventions

Intervention1: prolotherapy agent : dextrose bacteriostatic water lignocaine with adrenaline Control Intervention1: Acrylic splints: Anterior bite plant splint posterior bite plane splints

Eligibility

Inclusion criteria

Inclusion criteria: Patient with age group between 18 to 60 yrs, having Temporomandibular joint pain and clicking and not having any systemic and metabolic diseases

Exclusion criteria

Exclusion criteria: Patients having any systemic or metabolic diseases, Allergic to corn products, long term use of high doses of systemic steroids, patients age above 60 yrs and below 18 yrs and not having any TMJ pain and clicking

Design outcomes

Primary

Measure	Time frame
To reduce pain and improve mouth openingTimepoint: 1st day-first injection 2nd week 4th week 6th week	—

Secondary

Measure	Time frame
Assessment of reduction in pain and improvement in mouth openingTimepoint: Every 2 weeks up to 2 months after last injection for study group Every 2 weeks up to 2 months after delivering of splints for control group	—

Countries

India

Contacts

Public Contactsasikala B

srm dental college and hospital

sasiomfs@gmail.com9840495547

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026