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A clinical trail to study the effect of two drugs, propofol and etomidate on blood pressure and heart rate during anesthesia for spinal surgery.

A comparison of haemodynamic effects between induction agents propofol and etomidate in patients undergoing lumbar spinal surgeries

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/03/012447
Enrollment
70
Registered
2018-03-09
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients undergoing elective lumbar spinal surgeries

Interventions

Intervention1: Propofol: intravenous Propofol infusion 0.5 mg per kg per min during induction ( FROM TIME OF PROPOFOL ADMINISTATION UPTO LOSS OF EYE LASH REFLEX) Control Intervention1: Etomidate: int

Sponsors

Bangur Institute of Neurosciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: patients posted for elective lumbar spinal surgeries

Exclusion criteria

Exclusion criteria: Children Patients with known significant cardiac, respiratory, hepatic, renal, neurological diseases. Patient refusal . Haematological or endocrinal disorder. Known allergy to study drugs. Bleeding or coagulation abnormalities. Psychiatric disease. History of drug abuse. Mallampati Grade 3&4

Design outcomes

Primary

MeasureTime frame
Mean Arterial PressureTimepoint: before giving premedication, before induction of anesthesia, immediately after induction of anaesthesia, at intubation and 1, 3, and 5 min after intubation

Secondary

MeasureTime frame
Heart rate, Cardiac output, Bispectral indexTimepoint: before giving premedication, before induction of anesthesia, immediately after induction of anaesthesia, at intubation and 1, 3, and 5 min after intubation

Countries

India

Contacts

Public ContactSAIKAT NIYOGI

Bangur institute of neurosciences

saikatneuro1972@gmail.com9831732443

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026