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Assessment of role Calcium Gluconate for early reversal of neuromuscular blockade in Children after surgery

Pilot Study : Double Blind Randomized Controlled Trial for Comparison of Effect On Neuromuscular Blockade Recovery Between Calcium Gluconate Coadministered With Neostigmine and Neostigmine Only in Pediatric Patients

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2018/03/012386
Enrollment
100
Registered
2018-03-07
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- healthy patients in ASA (American Society of Anaesthesiology)I or II undergoing surgery

Interventions

None listed

Sponsors

AIIMS
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: (a) Children between the age group of 05 year to 15 yrs (b) ASA I and II

Exclusion criteria

Exclusion criteria: (a) Suspected difficult airway (b) History of bronchial asthma, neuromuscular disease or hepatic and renal disease. (c) Patient taking any medication known to influence the potency or duration of neuromuscular blocking agents. (d) Hypercalcemia (e) History of malignant hyperthermia, allergies to glycopyrrolate or neostigmine (f) Severe and significant congenital heart disease (g) Bleeding diathesis (h) Parental refusal (i) Weight

Design outcomes

Primary

MeasureTime frame
Primary end point will be neuromuscular recovery time (time from reversal administration to recovery of the TOF ratio to 0.9) Timepoint: 1—

Secondary

MeasureTime frame
Secondary end points will incude the TOFr at 5, 10,and 20 min after reversal administration and the incidence of PORC at each time point.Timepoint: 3—

Countries

India

Contacts

Public ContactPuneet Khanna

AIIMS,New Delhi

k.puneet@yahoo.com9873106516

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026