None listed
Conditions
Interventions
Intervention1: CurQfen: 250mg capsules 2 times in a day for 56 days
Control Intervention1: Placebo: 250mg capsules 2 times in a day for 56 days
Sponsors
Akay Flavours And Aromatics Pvt Ltd
Eligibility
Inclusion criteria
Inclusion criteria: 1.Chronic alcohol intake of more than six units per week. 1 unit is equal to 150 ml of wine or 360 ml of beer or 45 ml of 40 percentage alcohol 2.Mild to moderate cases of alcoholic hepatitis 3.Ratio of AST to ALT greater than 2 4.Informed consent
Exclusion criteria
Exclusion criteria: 1.Present with kidney failure (serum creatinine > 2.0 mg/dl) or in the process of renal dialysis 2.Present with Viral hepatitis (ALT level >/equal to 3 times the upper limit) 3.Receive any herbal medications or curcumin 4.Subjects abstaining from alcohol for more than 1 month 5. concomitant symptomatic or asymptomatic bacterial infection and severe bacterial infection within the previous 3 months. 6.Pregnancy or breastfeeding 7.Have a history of gall bladder diseases or removal
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| - reduction in liver enzymes - Changes in anti inflammatory markers - Changes in Antioxidant parametersTimepoint: Day 0, Day 56 | — |
Secondary
| Measure | Time frame |
|---|---|
| - Changes in Lipid Profile - Changes in Safety parameters/ Adverse eventsTimepoint: Day 0, Day 56 | — |
Countries
India
Contacts
Public ContactJestin V Thomas
Akay Flavours and Aromatics Pvt.Ltd
Outcome results
None listed