Skip to content

Comparative evaluation of branch retinal vein occlusion treatment with ultra wide-field imaging guided peripheral scatter laser in combination with ranibizumab ( anti-VEGF for macular edema in BRVO) vs ranibizumab only in treatment naive cases.

prospective randomized interventional trial comparing branch retinal vein occlusion treatment with ultra wide field imaging guided peripheral laser in combination with ranibizumab vs ranibizumab only in treatment naive cases.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/03/012383
Enrollment
30
Registered
2018-03-06
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- BRVO with macular edema

Interventions

Intervention1: ranibizumab and laser: treatment of brvo with macular edema with ranibizumab and laser Control Intervention1: ranibizumab only: treatment of brvo with macular edema with ranibizumab onl

Sponsors

AIIMS
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Diagnosed case of BRVO with macular edema with evidence of capillary non perfusion 2. Macular edema involving center of fovea 3. BCVA at baseline- 3/60-6/18 by Snellenâ??s visual acuity 4. Mean central subfield thickness > 300 micrometer by OCT at baseline visit 5. Informed consent 6. Media clarity, pupillary dilatation and patient cooperation sufficient for fundus photography

Exclusion criteria

Exclusion criteria: 1. other ocular diseases like AMD eyes, diabetic retinopathy, disc pallor 2. recent CVA, MI or major ischemic event 3 months preceding baseline visit 3. known sensitivity to any anti-VEGF drugs and sodium fluorescein 4. previous macular or pan retinal photocoagulation 5.previous anti-VEGF treatment 6.no consent 7.patient not willing for follow up

Design outcomes

Primary

MeasureTime frame
BCVA ( snellens visual acuity and ETDRS)Timepoint: 1 month, 3 months, 6 months

Secondary

MeasureTime frame
OCT number of ranibizumab injections contrast sensitivityTimepoint: 1 month, 3 months, 6 months

Countries

India

Contacts

Public ContactSiddhi Goel

AIIMS

maheshchandra04@gmail.com9868289233

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026