Health Condition 1: null- patients receiving re-Irradiation (reRT).
Conditions
Interventions
Intervention1: NA: NA
Control Intervention1: NA: NA
Sponsors
Nil
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients must have recurrence/ second primary (SPN) at least 6 months after prior radiotherapy. 2. Patients should have histopathological proof for both the primary tumor and at recurrence / second cancer in the head and neck region. 3. Patients should have been treated with radical intent for primary tumor with appropriate radical doses of radiation. 4. Patients who are diagnosed with recurrent or second cancer for which the radiation portals will overlap the fields of previously irradiated region. 5. In the recurrent setting the intention of treatment is radical.
Exclusion criteria
Exclusion criteria: 1.Patients having recurrence/ second primary (SPN) before completion of 6 months of prior radiotherapy. 2. Patients being treated with palliative intent in recurrent setting. 3. Radiation portals not overlapping the fields of previously irradiated region.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To document and evaluate change in quality of Life in patients receiving reRT for recurrence or second primary.Timepoint: After Completion of Radiation therapy | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.To evaluate changes in swallowing function, in patients receiving reRT. 2.To establish dosimetric relationship between Dysphagia Aspiration Related Structures and severity of swallowing dysfunction in patients receiving Re-RT. 3.To determine Incidence rate of acute and late toxicities associated with reRT. 4.To determine DFS/ local control rates/ OS rates from date of diagnosis of second primary/ recurrence. 5. To determine the pattern of disease progression post treatment in all patients.Timepoint: After Completion of Radiation therapy | — |
Countries
India
Contacts
Public ContactDr Carlton Johnny
Tata Memorial Hospital
Outcome results
None listed