Health Condition 1: null- Open heart surgerys
Conditions
Interventions
Intervention1: nil: nil
Sponsors
SVIMS
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age range: 18-65 years both male and female patients. 2. Undergoing coronary artery bypass grafting surgery (CABG) using the saphenous vein. 3. Undergoing cardiac valvular surgeries like aortic valve, mitral valve, combined valve surgeries (both aortic and mitral valve) with or without tricuspid annuloplasty. 4. Combined coronary artery and valve surgery. 5. American Society of Anesthesiologists Physical Status I, II & III.
Exclusion criteria
Exclusion criteria: 1. Patients undergoing CABG by the separation of the internal mammary artery (IMA) 2. Patients with the history of analgesic addiction or drug abuse 3. Patients with pre-existing pain syndrome 4. Patients undergoing redo surgery or surgical re-exploration during the study period 5. Patients who received repeated revisions due to infection 6. Patients with intensive care unit stay of more than 7 days due to respiratory complications and wound infection 7. Postoperative wound infection. 8. Patients with neurological pathologies 9. Patients treated with antidepressant medication 10. Severe cardiovascular dysfunction(New York Heart Association class III or IV 11. Severe pulmonary, renal and hepatic disease 12. Inability to communicate and understand NRS( numerical rating scale) 13. Patients not willing to participate in the study 14. Patients unwilling to cooperate or will be unreachable for phone interviews will also be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mutations will Identified , To analysis the levels of enzyme activity and m RNA levels.Timepoint: Mutations will be Identified , To analysis the levels of enzyme activity and m RNA levels with in two years. | — |
Secondary
| Measure | Time frame |
|---|---|
| Identified chronic persistent chronic painTimepoint: after three months | — |
Countries
India
Contacts
Public ContactDr Alok Samantaray
SVIMS Sri Venkateswara Institute Of Medical Sciences
Outcome results
None listed