Health Condition 1: null- Patients that are diagnosed with HIV with reliable index such as detection of HIV in plasma (viral load in plasma), ELISA or Western blot
Conditions
Interventions
None listed
Sponsors
iProcess Global Research Organization
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion Criteria for HIV donors: 1-At least 18 years old 2-Must be able to provide written informed consent or donors that have deceased their family must provide informed consent 3-Donors should be diagnosed with HIV with reliable index such as detection of HIV in plasma (viral load in plasma), ELISA or Western blot data in detection of p24, GP160 and/or GP41 protein and its antibody in plasma. 4-HIV status: both viremic and suppressed aviremic donors (viral load less than 50 copies/ml) treated with ART will be accepted. Inclusion Criteria for Healthy donors: 1-At least 18 years old 2-Must be able to provide written informed consent or donors that have deceased their family must provide informed consent. 3-Samples should be from healthy tissues (i.e. not cancerous or other condition currently receiving treatment).
Exclusion criteria
Exclusion criteria: Exclusion Criteria for HIV donors: 1-HIV donors who are co-infected with the hepatitis C virus 2-Active cancer Exclusion Criteria for Healthy donors: 1-Infected with HIV or other infectious disease including hepatitis C virus 2-Active cancer
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Determine which organ tissue cells contain HIV markers and the variance in distribution among the different tissues Timepoint: 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| â?¢ Determine the level of P24, cell associated HIV unspliced or multiple splicing RNA; proviral DNA reservoir size.Timepoint: 6 months | — |
Countries
India
Contacts
Public ContactDr Ramya Muthyala
iProcess Global Research Organization
Outcome results
None listed